How Ketamine Became The Drug Of Choice For Our Dissociated Moment
Technically speaking, ketamine is a dissociative anesthetic, meaning that it numbs your body and makes you feel apart from your environment — like you’re watching your own life happen instead of living it. But that doesn’t begin to capture the weirdness of what it feels like to get high on K.

The Big Business Of Loneliness
Capitalism abhors a vacuum, and into this collective social void has stepped a fleet of companies and entrepreneurs selling an end to social isolation. Over the past decade, on-demand connection has become both a big business and a powerful marketing opportunity.

Are Stem Cell Treatments A Type Of Miracle Cure Or Snake Oil?
Stem cells have taken on a mythic promise in the eyes of many who are ailing and desperate. But a new crop of treatments might be nothing more than costly placebos—or possibly dangerous.

The Wonder Drug for Aging, Made From One of the Deadliest Toxins on Earth
Botox is derived from a toxin purified from Clostridium botulinum, a bacterium that thrives and multiplies in faultily canned food. The botulinum toxin is so powerful that a tiny amount can suffocate a person by paralyzing the muscles used for breathing. That’s part of what protects Allergan’s $2.8 billion Botox empire.

The Price Of Plenty: How Beef Changed America
Exploitation and predatory pricing drove the transformation of the US beef industry – and created the model for modern agribusiness. The industrial slaughterhouse was a triumph of human ingenuity as well as a site of brutal labor exploitation.

The Key To Good Luck Is An Open Mind
What do these people have that the rest of us don’t? It turns out “ability” is the key word here. Beyond their level of privilege or the circumstances they were born into, the luckiest people may have a specific set of skills that bring chance opportunities their way.

The Dark Side Of Charisma
Charisma is a force that can rally people during difficult times, but it can also blind people and lead them to accept unwise actions, policies or conditions. And when it comes to leadership, political and professional, charisma matters more than we’d probably like to admit.

Ranking Veggie Chips By How Healthy They Are
“The darker-colored items with fewer ingredients will be the best.” This is because dark-colored vegetables are particularly rich in an assortment of plant compounds called phytochemicals, which help ward off diseases and tend to make them healthier than their lighter counterparts.

What We Know About Mental Fatigue
A temporary and localized fuel shortage triggers a rise in adenosine levels, which in turn blocks the release of neurotransmitters like dopamine. The result is a rise in perception of effort and a decrease in motivation—in other words, a feeling of mental fatigue.

Extreme Athleticism Is The New Midlife Crisis
Increasingly, people are responding to the anxieties of middle age not by clinging to the last vestiges of expiring youth but to taking on challenges that seem to belong to the young alone: by pushing the limits of what they’re physically capable of through endurance athletics and extreme fitness.

The Healing Power Of Nature
River guides might know that nature is transformative for the human body and psyche; but the mechanism behind such profound change is less universally agreed upon and understood. The idea that immersing yourself in forests and nature has a healing effect is far more than just folk wisdom.

How To Be Productive According To Ancient Philosophy
Productivity has been a topic of discussion ever since ancient eastern and western philosophy started. It’s a universal theme. I believe it’s in our nature to make better use of our time. Let’s start by learning the following 7 productivity lessons from the most well-known philosophers in history.

Four Japanese Rules To Live Past 100
Okinawa, long known as the island of the immortals, is home to the highest concentration of centenarians in Japan. The village of Kitanakagusuku ranks first in Japanese women’s longevity. What is it about this island that makes its inhabitants live a longer and happier life?

How Silicon Valley Ruined Work Culture
More and more offices are adopting the work culture invented by the technology upstarts. These are not the offices where your grandparents worked, clocking out at 5 sharp, eyeballing the corner office. There is no corner office here—just “hot desks” and open floor plans, wide as the prairie.

How To Get Up To Speed On Any Subject Quickly
When you’re in over your head, how do you quickly figure out what’s important? Is there a way to go from incompetent to in control—really, really fast? There is. Here’s how it works.

Behind The Scenes Of A Radical New Cancer Cure
CAR-T involves removing a patient’s own blood, filtering for immune cells called T-cells, and genetically engineering those cells to recognize and attack cancer. CAR-T made history in 2017 as the first FDA-approved gene therapy to treat any disease. The trials that led to approval showed response rates of 80 percent and above in aggressive leukemias and lymphomas that had resisted chemotherapy.

How Your Diet Affects Your Mental Health
Active people tend to overthink what food is doing for their body—Is keto good for endurance? What’s the perfect post-training macro spread? Butter or no butter in my coffee?—but underthink what it’s doing for their mind. Yet you’ve probably noticed that what you eat impacts what’s going on upstairs.

“Quadrangle”, How A Group Marriage Went Terribly Wrong
In 1969, two “conventional” married couples met, swapped partners, and lived in a group marriage, hoping to pioneer an alternative to divorce. It didn’t work. “Quadrangle” was directed by Amy Grappell.

It’s No Crime To Drink Wine By Yourself
From the moment we start to learn about wine, we are taught that drinking responsibly is a social activity. Wine is for sharing, for drinking with friends or family over a meal. But self-imposed isolation does not require you to forgo good food or good wine, despite the social stigma.

Success Comes From Affirming Your Potential
When people believe in their ability to grow, they make decisions that reflect this conviction, such as investing in their potential, focusing on their unique strengths, and discovering new paths to success and fulfillment that align with their core values and leadership goals.

Why You Shouldn’t Exercise To Lose Weight, Explained With 60+ Studies
We’ve been taught for years that as long as you hit the gym you can hit the buffet line and still lose weight. But there’s plenty of science out there to prove this statement false.